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Author Davidowitz, I.; Parmet, Y.; Frenkel-Toledo, S.; Banina, M.C.; Soroker, N.; Solomon, J.M.; Liebermann, D.G.; Levin, M.F.; Berman, S. url  doi
openurl 
  Title Relationship Between Spasticity and Upper-Limb Movement Disorders in Individuals With Subacute Stroke Using Stochastic Spatiotemporal Modeling Type Journal Article
  Year 2019 Publication (down) Neurorehabilitation and Neural Repair Abbreviated Journal Neurorehabil Neural Repair  
  Volume 33 Issue 2 Pages 141-152  
  Keywords Gaussian mixture model; Kullback-Liebler divergence; spasticity; stroke; upper-limb kinematics  
  Abstract BACKGROUND: Spasticity is common in patients with stroke, yet current quantification methods are insufficient for determining the relationship between spasticity and voluntary movement deficits. This is partly a result of the effects of spasticity on spatiotemporal characteristics of movement and the variability of voluntary movement. These can be captured by Gaussian mixture models (GMMs). OBJECTIVES: To determine the influence of spasticity on upper-limb voluntary motion, as assessed by the bidirectional Kullback-Liebler divergence (BKLD) between motion GMMs. METHODS: A total of 16 individuals with subacute stroke and 13 healthy aged-equivalent controls reached to grasp 4 targets (near-center, contralateral, far-center, and ipsilateral). Two-dimensional GMMs (angle and time) were estimated for elbow extension motion. BKLD was computed for each individual and target, within the control group and between the control and stroke groups. Movement time, final elbow angle, average elbow velocity, and velocity smoothness were computed. RESULTS: Between-group BKLDs were much larger than within control-group BKLDs. Between-group BKLDs for the near-center target were lower than those for the far-center and contralateral targets, but similar to that for the ipsilateral target. For those with stroke, the final angle was lower for the near-center target, and the average velocity was higher. Velocity smoothness was lower for the near-center than for the ipsilateral target. Elbow flexor and extensor passive muscle resistance (Modified Ashworth Scale) strongly explained BKLD values. CONCLUSIONS: Results support the view that individuals with poststroke spasticity have a velocity-dependent reduction in active elbow joint range and that BKLD can be used as an objective measure of the effects of spasticity on reaching kinematics.  
  Address 1 Ben-Gurion University of the Negev, Beer-Sheva, Israel  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 1545-9683 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30744528 Approved no  
  Call Number Serial 93  
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Author Frenkel-Toledoa, S.; Bentin, S.; Perry, A.; Liebermann, D. G.; Soroker, N. doi  openurl
  Title Mirror-neuron system recruitment by action observation: Effects of focal brain damage on mu suppression Type Journal Article
  Year 2014 Publication (down) NeuroImage Abbreviated Journal  
  Volume 87 Issue Pages 127-137  
  Keywords  
  Abstract Mu suppression is the attenuation of EEG power in the alpha frequency range (8-12 Hz), recorded over the sensorimotor cortex during execution and observation of motor actions. Based on this dual characteristic it is thought to signalize activation of a human analogue of the mirror neuron system (MNS) found in macaque monkeys, though much uncertainty remains concerning its specificity and full significance. To further explore the hypothesized relationship between mu suppression and MNS activation, we investigated how it is affected by damage to cortical regions, including areas where the MNS is thought to reside. EEG was recorded in 33 first-event stroke patients during observation of video-clips showing reaching and grasping hand movements. We examined the modulation of EEG oscillations at central and occipital sites, and analyzed separately the lower (8-10 Hz) and higher (10-12 Hz) segments of the alpha/mu range. Suppression was determined relative to observation of a non-biological movement. Normalized lesion data were used to investigate how damage to regions of the fronto-parietal cortex affects the pattern of suppression. The magnitude of mu suppression during action observation was significantly reduced in the affected hemisphere compared to the unaffected hemisphere. Differences between the hemispheres were significant at central (sensorimotor) sites but not at occipital (visual) sites. Total hemispheric volume loss did not correlate with mu suppression. Suppression in the lower mu range in the unaffected hemisphere (C3) correlated with lesion extent within the right inferior parietal cortex. Our lesion study supports the role of mu suppression as a marker of MNS activation, as suggested by findings gathered in previous studies in normal subjects.  
  Address  
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  Notes Approved no  
  Call Number Serial 71  
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Author Falk, B.; Eliakim, A.; Dotan, R.; Liebermann, D.G.; Regev, R.; Bar-Or, O. url  openurl
  Title Birth weight and physical ability in 5- to 8-yr-old healthy children born prematurely Type Journal Article
  Year 1997 Publication (down) Medicine and Science in Sports and Exercise Abbreviated Journal Med Sci Sports Exerc  
  Volume 29 Issue 9 Pages 1124-1130  
  Keywords *Birth Weight; Child; Child Development/physiology; Child, Preschool; Female; Follow-Up Studies; Humans; Infant, Newborn; *Infant, Premature; Male; *Motor Skills; *Physical Fitness  
  Abstract Recent advances in perinatal care have resulted in increased survival rates of extremely small and immature newborns. This has resulted in some neurodevelopmental impairment. The purpose of this study was to quantitatively evaluate and compare neuromuscular performance in children born prematurely at various levels of subnormal birth weight (BW). Subjects were 5- to 8-yr-old children born prematurely at different levels of subnormal BW (535-1760 g, N = 22, PM), and age-matched controls born at full term (> 2500 g, N = 15, CON). None of the subjects had any clinically defined neuromuscular disabilities. Body mass (BM) of PM was lower than that of CON (18.3 +/- 2.7 vs 21.7 +/- 3.8 kg) with no difference in height or sum of 4 skinfolds. Peak mechanical power output determined with a 15-s modified Wingate Anaerobic Test and corrected for BM was lower (P = 0.07) in PM than in CON (5.11 +/- 1.07 vs 5.94 +/- 1.00 W.kg-1). This was especially noticeable in children born at extremely low BW (ELBW, < 1000 g, 4.49 +/- 1.04 W.kg-1, P < 0.01). Peak power, determined in a force-plate vertical jump, corrected for BM was lower in PM vs CON (25.5 +/- 5.4 vs 30.8 +/- 5.2 W.kg-1, respectively P = 0.01), especially in the ELBW group (20.0 +/- 5.5 W.kg-1). Similarly, the elapsed time between peak velocity and actual jump take-off was longer in PM than in CON (41.2 +/- 9.4 vs 35.8 +/- 5.8 ms, respectively, P = 0.04). No differences were observed in peak force. The results suggest that performance deficiencies of prematurely-born children may be a result of inferior inter-muscular coordination. The precise neuromotor factors responsible for this should be identified by future research.  
  Address Ribstein Center for Research and Sport Medicine Sciences, Wingate Institute, Netanya, Israel. bfalk@ccsg.tau.ac.il  
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  ISSN 0195-9131 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:9309621 Approved no  
  Call Number Serial 64  
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Author Liebermann, D.G.; Katz, L.; Hughes, M.D.; Bartlett, R.M.; McClements, J.; Franks, I.M. url  doi
openurl 
  Title Advances in the application of information technology to sport performance Type Journal Article
  Year 2002 Publication (down) Journal of Sports Sciences Abbreviated Journal J Sports Sci  
  Volume 20 Issue 10 Pages 755-769  
  Keywords *Biofeedback, Psychology; *Computer Simulation; Humans; Models, Biological; Physical Education and Training/*methods; Psychomotor Performance/physiology; Sports Medicine/methods; *Task Performance and Analysis; Videotape Recording  
  Abstract This paper overviews the diverse information technologies that are used to provide athletes with relevant feedback. Examples taken from various sports are used to illustrate selected applications of technology-based feedback. Several feedback systems are discussed, including vision, audition and proprioception. Each technology described here is based on the assumption that feedback would eventually enhance skill acquisition and sport performance and, as such, its usefulness to athletes and coaches in training is critically evaluated.  
  Address Department of Physical Therapy, Sackler Faculty of Medicine, University of Tel Aviv, Israel  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0264-0414 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12363293 Approved no  
  Call Number Serial 40  
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Author Issurin, V.B.; Liebermann, D.G.; Tenenbaum, G. url  doi
openurl 
  Title Effect of vibratory stimulation training on maximal force and flexibility Type
  Year 1994 Publication (down) Journal of Sports Sciences Abbreviated Journal J Sports Sci  
  Volume 12 Issue 6 Pages 561-566  
  Keywords Adult; Humans; Male; Muscle Contraction/physiology; Muscle, Skeletal/*physiology; *Physical Education and Training; Vibration/*therapeutic use  
  Abstract In this study, we investigated a new method of training for maximal strength and flexibility, which included exertion with superimposed vibration (vibratory stimulation, VS) on target muscles. Twenty-eight male athletes were divided into three groups, and trained three times a week for 3 weeks in one of the following conditions: (A) conventional exercises for strength of the arms and VS stretching exercises for the legs; (B) VS strength exercises for the arms and conventional stretching exercises for the legs; (C) irrelevant training (control group). The vibration was applied at 44 Hz while its amplitude was 3 mm. The effect of training was evaluated by means of isotonic maximal force, heel-to-heel length in the two-leg split across, and flex-and-reach test for body flexion. The VS strength training yielded an average increase in isotonic maximal strength of 49.8%, compared with an average gain of 16% with conventional training, while no gain was observed for the control group. The VS flexibility training resulted in an average gain in the legs split of 14.5 cm compared with 4.1 cm for the conventional training and 2 cm for the control groups, respectively. The ANOVA revealed significant pre-post training effects and an interaction between pre-post training and 'treatment' effects (P < 0.001) for the isotonic maximal force and both flexibility tests. It was concluded that superimposed vibrations applied for short periods allow for increased gains in maximal strength and flexibility.  
  Address Ribstein Centre for Research and Sport Medicine Sciences, Wingate Institute, Wingate Post, Israel  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 0264-0414 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:7853452 Approved no  
  Call Number Serial 56  
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