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Author Uri, O.; Pritsch, M.; Oran, A.; Liebermann, D.G. url  doi
openurl 
  Title Upper limb kinematics after arthroscopic and open shoulder stabilization Type Journal Article
  Year 2014 Publication Journal of Shoulder and Elbow Surgery Abbreviated Journal Journal of Shoulder and Elbow Surgery  
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  Series Volume Series Issue Edition  
  ISSN 1058-2746 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number Serial 75  
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Author Frenkel-Toledo, S.; Liebermann, D.G.; Bentin, S.; Soroker, N. url  doi
openurl 
  Title Dysfunction of the Human Mirror Neuron System in Ideomotor Apraxia: Evidence from Mu Suppression Type Journal Article
  Year 2016 Publication Journal of Cognitive Neuroscience Abbreviated Journal J Cogn Neurosci  
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  Abstract Stroke patients with ideomotor apraxia (IMA) have difficulties controlling voluntary motor actions, as clearly seen when asked to imitate simple gestures performed by the examiner. Despite extensive research, the neurophysiological mechanisms underlying failure to imitate gestures in IMA remain controversial. The aim of the current study was to explore the relationship between imitation failure in IMA and mirror neuron system (MNS) functioning. Mirror neurons were found to play a crucial role in movement imitation and in imitation-based motor learning. Their recruitment during movement observation and execution is signaled in EEG recording by suppression of the lower (8-10 Hz) mu range. We examined the modulation of EEG in this range in stroke patients with left (n = 21) and right (n = 15) hemisphere damage during observation of video clips showing different manual movements. IMA severity was assessed by the DeRenzi's standardized diagnostic test. Results showed that failure to imitate observed manual movements correlated with diminished mu suppression in patients with damage to the right inferior parietal lobule and in patients with damage to the right inferior frontal gyrus pars opercularis-areas where major components of the human MNS are assumed to reside. Voxel-based lesion symptom mapping revealed a significant impact on imitation capacity for the left inferior and superior parietal lobules and the left post central gyrus. Both left and right hemisphere damages were associated with imitation failure typical of IMA, yet a clear demonstration of relationship to the MNS was obtained only in the right hemisphere damage group. Suppression of the 8-10 Hz range was stronger in central compared with occipital sites, pointing to a dominant implication of mu rather than alpha rhythms. However, the suppression correlated with De Renzi's apraxia test scores not only in central but also in occipital sites, suggesting a multifactorial mechanism for IMA, with a possible impact for deranged visual attention (alpha suppression) beyond the effect of MNS damage (mu suppression).  
  Address Loewenstein Hospital, Ra'anana, Israel  
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  ISSN 0898-929X ISBN Medium  
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  Notes PMID:26942323 Approved no  
  Call Number Serial 82  
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Author Grip, H.; Tengman, E.; Liebermann, D.G.; Hager, C.K. url  doi
openurl 
  Title Kinematic analyses including finite helical axes of drop jump landings demonstrate decreased knee control long after anterior cruciate ligament injury Type Journal Article
  Year 2019 Publication PloS one Abbreviated Journal PLoS One  
  Volume 14 Issue 10 Pages e0224261  
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  Abstract The purpose was to evaluate the dynamic knee control during a drop jump test following injury of the anterior cruciate ligament injury (ACL) using finite helical axes. Persons injured 17-28 years ago, treated with either physiotherapy (ACLPT, n = 23) or reconstruction and physiotherapy (ACLR, n = 28) and asymptomatic controls (CTRL, n = 22) performed a drop jump test, while kinematics were registered by motion capture. We analysed the Preparation phase (from maximal knee extension during flight until 50 ms post-touchdown) followed by an Action phase (until maximal knee flexion post-touchdown). Range of knee motion (RoM), and the length of each phase (Duration) were computed. The finite knee helical axis was analysed for momentary intervals of ~15 degrees of knee motion by its intersection (DeltaAP position) and inclination (DeltaAP Inclination) with the knee's Anterior-Posterior (AP) axis. Static knee laxity (KT100) and self-reported knee function (Lysholm score) were also assessed. The results showed that both phases were shorter for the ACL groups compared to controls (CTRL-ACLR: Duration 35+/-8 ms, p = 0.000, CTRL-ACLPT: 33+/-9 ms, p = 0.000) and involved less knee flexion (CTRL-ACLR: RoM 6.6+/-1.9 degrees , p = 0.002, CTRL-ACLR: 7.5 +/-2.0 degrees , p = 0.001). Low RoM and Duration correlated significantly with worse knee function according to Lysholm and higher knee laxity according to KT-1000. Three finite helical axes were analysed. The DeltaAP position for the first axis was most anterior in ACLPT compared to ACLR (DeltaAP position -1, ACLPT-ACLR: 13+/-3 mm, p = 0.004), with correlations to KT-1000 (rho 0.316, p = 0.008), while the DeltaAP inclination for the third axis was smaller in the ACLPT group compared to controls (DeltaAP inclination -3 ACLPT-CTRL: -13+/-5 degrees , p = 0.004) and showed a significant side difference in ACL injured groups during Action (Injured-Non-injured: 8+/-2.7 degrees , p = 0.006). Small DeltaAP inclination -3 correlated with low Lysholm (rho 0.391, p = 0.002) and high KT-1000 (rho -0.450, p = 0.001). Conclusions Compensatory movement strategies seem to be used to protect the injured knee during landing. A decreased DeltaAP inclination in injured knees during Action suggests that the dynamic knee control may remain compromised even long after injury.  
  Address Department of Community Medicine and Rehabilitation, Physiotherapy, Umea University, Umea, Sweden  
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  ISSN 1932-6203 ISBN Medium  
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  Notes PMID:31671111 Approved no  
  Call Number Serial 102  
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Author Frenkel-Toledo, S.; Levin, M.F.; Berman, S.; Liebermann, D.G.; Baniña, M.C.; Solomon, J.M.; Ofir-Geva, S.; Soroker, N. url  doi
openurl 
  Title Shared and distinct voxel-based lesion-symptom mappings for spasticity and impaired movement in the hemiparetic upper limb Type Journal Article
  Year 2022 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 12 Issue 1 Pages  
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  ISSN 2045-2322 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number Serial 113  
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