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Author Davidowitz, I.; Parmet, Y.; Frenkel-Toledo, S.; Banina, M.C.; Soroker, N.; Solomon, J.M.; Liebermann, D.G.; Levin, M.F.; Berman, S. url  doi
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  Title Relationship Between Spasticity and Upper-Limb Movement Disorders in Individuals With Subacute Stroke Using Stochastic Spatiotemporal Modeling Type Journal Article
  Year 2019 Publication Neurorehabilitation and Neural Repair Abbreviated Journal Neurorehabil Neural Repair  
  Volume (down) 33 Issue 2 Pages 141-152  
  Keywords Gaussian mixture model; Kullback-Liebler divergence; spasticity; stroke; upper-limb kinematics  
  Abstract BACKGROUND: Spasticity is common in patients with stroke, yet current quantification methods are insufficient for determining the relationship between spasticity and voluntary movement deficits. This is partly a result of the effects of spasticity on spatiotemporal characteristics of movement and the variability of voluntary movement. These can be captured by Gaussian mixture models (GMMs). OBJECTIVES: To determine the influence of spasticity on upper-limb voluntary motion, as assessed by the bidirectional Kullback-Liebler divergence (BKLD) between motion GMMs. METHODS: A total of 16 individuals with subacute stroke and 13 healthy aged-equivalent controls reached to grasp 4 targets (near-center, contralateral, far-center, and ipsilateral). Two-dimensional GMMs (angle and time) were estimated for elbow extension motion. BKLD was computed for each individual and target, within the control group and between the control and stroke groups. Movement time, final elbow angle, average elbow velocity, and velocity smoothness were computed. RESULTS: Between-group BKLDs were much larger than within control-group BKLDs. Between-group BKLDs for the near-center target were lower than those for the far-center and contralateral targets, but similar to that for the ipsilateral target. For those with stroke, the final angle was lower for the near-center target, and the average velocity was higher. Velocity smoothness was lower for the near-center than for the ipsilateral target. Elbow flexor and extensor passive muscle resistance (Modified Ashworth Scale) strongly explained BKLD values. CONCLUSIONS: Results support the view that individuals with poststroke spasticity have a velocity-dependent reduction in active elbow joint range and that BKLD can be used as an objective measure of the effects of spasticity on reaching kinematics.  
  Address 1 Ben-Gurion University of the Negev, Beer-Sheva, Israel  
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  ISSN 1545-9683 ISBN Medium  
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  Notes PMID:30744528 Approved no  
  Call Number Serial 93  
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Author Liebermann, D.G.; Issurin V. openurl 
  Title Effects of vibratory stimulation on the perception of effort during isotonic contractions Type Journal Article
  Year 1997 Publication Journal of Human Movement Studies Abbreviated Journal  
  Volume (down) 32 Issue Pages 171-186  
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  Call Number Serial 61  
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Author Falk, B.; Eliakim, A.; Dotan, R.; Liebermann, D.G.; Regev, R.; Bar-Or, O. url  openurl
  Title Birth weight and physical ability in 5- to 8-yr-old healthy children born prematurely Type Journal Article
  Year 1997 Publication Medicine and Science in Sports and Exercise Abbreviated Journal Med Sci Sports Exerc  
  Volume (down) 29 Issue 9 Pages 1124-1130  
  Keywords *Birth Weight; Child; Child Development/physiology; Child, Preschool; Female; Follow-Up Studies; Humans; Infant, Newborn; *Infant, Premature; Male; *Motor Skills; *Physical Fitness  
  Abstract Recent advances in perinatal care have resulted in increased survival rates of extremely small and immature newborns. This has resulted in some neurodevelopmental impairment. The purpose of this study was to quantitatively evaluate and compare neuromuscular performance in children born prematurely at various levels of subnormal birth weight (BW). Subjects were 5- to 8-yr-old children born prematurely at different levels of subnormal BW (535-1760 g, N = 22, PM), and age-matched controls born at full term (> 2500 g, N = 15, CON). None of the subjects had any clinically defined neuromuscular disabilities. Body mass (BM) of PM was lower than that of CON (18.3 +/- 2.7 vs 21.7 +/- 3.8 kg) with no difference in height or sum of 4 skinfolds. Peak mechanical power output determined with a 15-s modified Wingate Anaerobic Test and corrected for BM was lower (P = 0.07) in PM than in CON (5.11 +/- 1.07 vs 5.94 +/- 1.00 W.kg-1). This was especially noticeable in children born at extremely low BW (ELBW, < 1000 g, 4.49 +/- 1.04 W.kg-1, P < 0.01). Peak power, determined in a force-plate vertical jump, corrected for BM was lower in PM vs CON (25.5 +/- 5.4 vs 30.8 +/- 5.2 W.kg-1, respectively P = 0.01), especially in the ELBW group (20.0 +/- 5.5 W.kg-1). Similarly, the elapsed time between peak velocity and actual jump take-off was longer in PM than in CON (41.2 +/- 9.4 vs 35.8 +/- 5.8 ms, respectively, P = 0.04). No differences were observed in peak force. The results suggest that performance deficiencies of prematurely-born children may be a result of inferior inter-muscular coordination. The precise neuromotor factors responsible for this should be identified by future research.  
  Address Ribstein Center for Research and Sport Medicine Sciences, Wingate Institute, Netanya, Israel. bfalk@ccsg.tau.ac.il  
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  ISSN 0195-9131 ISBN Medium  
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  Notes PMID:9309621 Approved no  
  Call Number Serial 64  
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Author Biess, A.; Liebermann, D.G.; Flash, T. url  doi
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  Title A computational model for redundant human three-dimensional pointing movements: integration of independent spatial and temporal motor plans simplifies movement dynamics Type Journal Article
  Year 2007 Publication The Journal of Neuroscience : the Official Journal of the Society for Neuroscience Abbreviated Journal J Neurosci  
  Volume (down) 27 Issue 48 Pages 13045-13064  
  Keywords Analysis of Variance; Arm/physiology; Biomechanics; *Computer Simulation; Humans; *Models, Biological; Movement/*physiology; *Nonlinear Dynamics; Posture/physiology; Psychomotor Performance/*physiology; Range of Motion, Articular/physiology; Reaction Time/physiology; Space Perception/*physiology; Time Factors; Torque  
  Abstract Few computational models have addressed the spatiotemporal features of unconstrained three-dimensional (3D) arm motion. Empirical observations made on hand paths, speed profiles, and arm postures during point-to-point movements led to the assumption that hand path and arm posture are independent of movement speed, suggesting that the geometric and temporal properties of movements are decoupled. In this study, we present a computational model of 3D movements for an arm with four degrees of freedom based on the assumption that optimization principles are separately applied at the geometric and temporal levels of control. Geometric properties (path and posture) are defined in terms of geodesic paths with respect to the kinetic energy metric in the Riemannian configuration space. Accordingly, a geodesic path can be generated with less muscular effort than on any other, nongeodesic path, because the sum of all configuration-speed-dependent torques vanishes. The temporal properties of the movement (speed) are determined in task space by minimizing the squared jerk along the selected end-effector path. The integration of both planning levels into a single spatiotemporal representation simplifies the control of arm dynamics along geodesic paths and results in movements with near minimal torque change and minimal peak value of kinetic energy. Thus, the application of Riemannian geometry allows for a reconciliation of computational models previously proposed for the description of arm movements. We suggest that geodesics are an emergent property of the motor system through the exploration of dynamical space. Our data validated the predictions for joint trajectories, hand paths, final postures, speed profiles, and driving torques.  
  Address Department of Mathematics, Weizmann Institute of Science, 76100 Rehovot, Israel. armin.biess@weizmann.ac.il  
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  ISSN 0270-6474 ISBN Medium  
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  Notes PMID:18045899 Approved no  
  Call Number Serial 35  
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Author Tenenbaum, G.; Kohler, N.; Shraga, S.; Liebermann, D.G.; Lidor, R. openurl 
  Title Anticipation and confidence of decisions related to skilled performance Type Journal Article
  Year 1996 Publication Journal of Sport Psychology Abbreviated Journal  
  Volume (down) 27 Issue Pages 293-307  
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  Abstract This study was carried out to examine anticipatory decisions of novice, intermediate, and expert tennis players and the confidence with which these decisions are made by these athletes. Perceived eye-focus was also measured to verify whether it is related to expertise level prior to action execution. Forty-five Australian players, 15 in each skill category, were exposed to 6 temporal occluded film conditions (480, 320, 160 ms prior to racquet-ball contact, at contact, and 160 and 320 ms after contact) in randomized order within 8 tennis strokes. In each condition, after viewing the filmed sequence, they were asked to report the final ball location of the opponent's stroke, how confident they were in this decision, and their perceived eye-focus location during the sequence. Experts and intermediates were superior in anticipatory decisions to their counterparts, only under short exposure durations. Novices showed more confidence than experts and intermediates at the beginning of the sequence, but after 160 and 320 ms of ball-racquet contact, experts were much more confident than novices, and intermediates. Self-reported eye-focus differed substantially with respect to expertise level. While experts attended to several locations prior to ball-racquet contact, intermediate and novice players gazed at one location. After contact, the reverse was evident. The findings are in partial agreement with other studies which have applied the temporal occlusion paradigm to study expert-novice differences in anticipatory skills.  
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  Call Number Serial 59  
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