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	Author	Levin, M.F.; Berman, S.; Weiss, N.; Parmet, Y.; Banina, M.C.; Frenkel-Toledo, S.; Soroker, N.; Solomon, J.M.; Liebermann, D.G.
	Title	ENHANCE proof-of-concept three-arm randomized trial: effects of reaching training of the hemiparetic upper limb restricted to the spasticity-free elbow range			Type
	Year	2023	Publication	Scientific Reports	Abbreviated Journal	Sci Rep
	Volume	13	Issue	1	Pages	22934
	Keywords	Humans; Elbow; Transcranial Direct Current Stimulation; Muscle Spasticity/therapy/complications; Upper Extremity; Elbow Joint; Stroke/complications; Stroke Rehabilitation/methods
	Abstract	Post-stroke motor recovery processes remain unknown. Timescales and patterns of upper-limb (UL) recovery suggest a major impact of biological factors, with modest contributions from rehabilitation. We assessed a novel impairment-based training motivated by motor control theory where reaching occurs within the spasticity-free elbow range. Patients with subacute stroke (</= 6 month; n = 46) and elbow flexor spasticity were randomly allocated to a 10-day UL training protocol, either personalized by restricting reaching to the spasticity-free elbow range defined by the tonic stretch reflex threshold (TSRT) or non-personalized (non-restricted) and with/without anodal transcranial direct current stimulation. Outcomes assessed before, after, and 1 month post-intervention were elbow flexor TSRT angle and reach-to-grasp arm kinematics (primary) and stretch reflex velocity sensitivity, clinical impairment, and activity (secondary). Results were analyzed for 3 groups as well as those of the effects of impairment-based training. Clinical measures improved in both groups. Spasticity-free range training resulted in faster and smoother reaches, smaller (i.e., better) arm-plane path length, and closer-to-normal shoulder/elbow movement patterns. Non-personalized training improved clinical scores without improving arm kinematics, suggesting that clinical measures do not account for movement quality. Impairment-based training within a spasticity-free elbow range is promising since it may improve clinical scores together with arm movement quality.Clinical Trial Registration: URL: http://www.clinicaltrials.gov . Unique Identifier: NCT02725853; Initial registration date: 01/04/2016.
	Address	Department of Physical Therapy, Faculty of Medicine, Stanley Steyer School of Health Professions, Tel Aviv University, POB 39040, 61390, Ramat Aviv, Tel Aviv, Israel. dlieberm@tauex.tau.ac.il
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	2045-2322	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:38129527; PMCID:PMC10739929			Approved	no
	Call Number				Serial	121
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	Author	Salzer, Y.; Friedman, J.
	Title	Reaching trajectories unravel modality-dependent temporal dynamics of the automatic process in the Simon task: a model-based approach			Type	Journal Article
	Year	2020	Publication	Psychological Research	Abbreviated Journal	Psychol Res
	Volume	84	Issue	6	Pages	1700-1713
	Keywords
	Abstract	The Simon effect represents a phenomenon in which the location of the stimuli affects the speed and accuracy of the response, despite being irrelevant for the task demands. This is believed to be due to an automatic activation of a response corresponding to the location of the stimuli, which conflicts with the controlled decision process based on relevant stimuli features. Previously, differences in the nature of the Simon effect (i.e., the pattern of change of the effect across the distribution of response times) between visual and somatosensory stimuli were reported. We hypothesize that the temporal dynamics of visual and somatosensory automatic and controlled processes vary, thus driving the reported behavioral differences. While most studies have used response times to study the underlying mechanisms involved, in this study we had participants reach out to touch the targets and recorded their arm movements using a motion capture system. Importantly, the participants started their movements before a final decision was made. In this way, we could analyze the movements to gain insights into the competition between the automatic and controlled processes. We used this technique to describe the results in terms of a model assuming automatic activation due to location-based evidence, followed by inhibition. We found that for the somatosensory Simon effect, the decay of the automatic process is significantly slower than for the visual Simon effect, suggesting quantitative differences in this automatic process between the visual and somatosensory modalities.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0340-0727	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:30980236			Approved	no
	Call Number				Serial	97
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	Author	Kaufman-Cohen, Y.; Levanon, Y.; Friedman, J.; Yaniv, Y.; Portnoy, S.
	Title	Home exercise in the dart-throwing motion plane after distal radius fractures: A Pilot Randomized Controlled Trial			Type	Journal Article
	Year	2020	Publication	Journal of Hand Therapy	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	no
	Call Number				Serial	103
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	Author	Krasovsky, T.; Weiss, P.L.; Zuckerman, O.; Bar, A.; Keren-Capelovitch, T.; Friedman, J.
	Title	DataSpoon: Validation of an Instrumented Spoon for Assessment of Self-Feeding			Type	Journal Article
	Year	2020	Publication	Sensors (Basel, Switzerland)	Abbreviated Journal	Sensors (Basel)
	Volume	20	Issue	7	Pages
	Keywords	concurrent validity; feasibility; kinematics; outcome assessment; rehabilitation
	Abstract	Clinically feasible assessment of self-feeding is important for adults and children with motor impairments such as stroke or cerebral palsy. However, no validated assessment tool for self-feeding kinematics exists. This work presents an initial validation of an instrumented spoon (DataSpoon) developed as an evaluation tool for self-feeding kinematics. Ten young, healthy adults (three male; age 27.2 +/- 6.6 years) used DataSpoon at three movement speeds (slow, comfortable, fast) and with three different grips: “natural”, power and rotated power grip. Movement kinematics were recorded concurrently using DataSpoon and a magnetic motion capture system (trakSTAR). Eating events were automatically identified for both systems and kinematic measures were extracted from yaw, pitch and roll (YPR) data as well as from acceleration and tangential velocity profiles. Two-way, mixed model Intraclass correlation coefficients (ICC) and 95% limits of agreement (LOA) were computed to determine agreement between the systems for each kinematic variable. Most variables demonstrated fair to excellent agreement. Agreement for measures of duration, pitch and roll exceeded 0.8 (excellent agreement) for >80% of speed and grip conditions, whereas lower agreement (ICC < 0.46) was measured for tangential velocity and acceleration. A bias of 0.01-0.07 s (95% LOA [-0.54, 0.53] to [-0.63, 0.48]) was calculated for measures of duration. DataSpoon enables automatic detection of self-feeding using simple, affordable movement sensors. Using movement kinematics, variables associated with self-feeding can be identified and aid clinical reasoning for adults and children with motor impairments.
	Address	Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	1424-8220	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:32283624; PMCID:PMC7180859			Approved	no
	Call Number				Serial	104
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	Author	Zacks, O.; Friedman, J.
	Title	Analogies can speed up the motor learning process			Type	Journal Article
	Year	2020	Publication	Scientific Reports	Abbreviated Journal	Sci Rep
	Volume	10	Issue	1	Pages	6932
	Keywords
	Abstract	Analogies have been shown to improve motor learning in various tasks and settings. In this study we tested whether applying analogies can shorten the motor learning process and induce insight and skill improvement in tasks that usually demand many hours of practice. Kinematic measures were used to quantify participant's skill and learning dynamics. For this purpose, we used a drawing task, in which subjects drew lines to connect dots, and a mirror game, in which subjects tracked a moving stimulus. After establishing a baseline, subjects were given an analogy, explicit instructions or no further instruction. We compared their improvement in skill (quantified by coarticulation or smoothness), accuracy and movement duration. Subjects in the analogy and explicit groups improved their coarticulation in the target task, while significant differences were found in the mirror game only at a slow movement frequency between analogy and controls.We conclude that a verbal analogy can be a useful tool for rapidly changing motor kinematics and movement strategy in some circumstances, although in the tasks selected it did not produce better performance in most measurements than explicit guidance. Furthermore, we observed that different movement facets may improve independently from others, and may be selectively affected by verbal instructions. These results suggest an important role for the type of instruction in motor learning.
	Address	Dept. of Physical Therapy, Stanley Steyer School of Health Professions, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	2045-2322	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:32332826; PMCID:PMC7181737			Approved	no
	Call Number	Penn State @ write.to.jason @			Serial	105
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