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Author Frenkel-Toledo, S.; Levin, M.F.; Berman, S.; Liebermann, D.G.; Baniña, M.C.; Solomon, J.M.; Ofir-Geva, S.; Soroker, N. url  doi
openurl 
  Title Shared and distinct voxel-based lesion-symptom mappings for spasticity and impaired movement in the hemiparetic upper limb Type Journal Article
  Year 2022 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 12 Issue 1 Pages  
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  Series Volume Series Issue Edition  
  ISSN 2045-2322 ISBN Medium  
  Area Expedition Conference  
  Notes (up) Approved no  
  Call Number Serial 113  
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Author Swissa, Y.; Hacohen, S.; Friedman, J.; Frenkel-Toledo, S. pdf  url
doi  openurl
  Title Sensorimotor performance after high-definition transcranial direct current stimulation over the primary somatosensory or motor cortices in men versus women Type Journal Article
  Year 2022 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 12 Issue Pages 11117  
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  Abstract The primary somatosensory (S1) cortex is a central structure in motor performance. However, transcranial direct current stimulation (tDCS) research aimed at improving motor performance usually targets the primary motor cortex (M1). Recently, sex was found to mediate tDCS response. Thus, we investigated whether tDCS with an anodal electrode placed over S1 improves motor performance and sensation perception in men versus women. Forty-five participants randomly received 15-min high-definition tDCS (HD-tDCS) at 1 mA to S1, M1, or sham stimulation. Reaching performance was tested before and immediately following stimulation. Two-point orientation discrimination (TPOD) of fingers and proprioception of a reaching movement were also tested. Although motor performance did not differ between groups, reaching reaction time improved in the M1 group men. Reaching movement time and endpoint error improved in women and men, respectively. Correct trials percentage for TPOD task was higher in the S1 compared to the M1 group in the posttest and improved only in the S1 group. Reaching movement time for the proprioception task improved, overall, and endpoint error did not change. Despite the reciprocal connections between S1 and M1, effects of active tDCS over S1 and M1 may specifically influence sensation perception and motor performance, respectively. Also, sex may mediate effects of HD-tDCS on motor performance.  
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  ISSN 2045-2322 ISBN Medium  
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  Notes (up) Approved no  
  Call Number Serial 114  
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Author Thorpe, A.; Friedman, J.; Evans, S.; Nesbitt, K.; Eidels, A. pdf  url
doi  openurl
  Title Mouse Movement Trajectories as an Indicator of Cognitive Workload Type Journal Article
  Year 2022 Publication International Journal of Human-Computer Interaction Abbreviated Journal International Journal of Human-Computer Interaction  
  Volume 38 Issue 15 Pages 1464-1479  
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  Abstract Assessing the cognitive impact of user interfaces is a shared focus of human-computer interaction researchers and cognitive scientists. Methods of cognitive assessment based on data derived from the system itself, rather than external apparatus, have the potential to be applied in a range of scenarios. The current study applied methods of analyzing kinematics to mouse movements in a computer-based task, alongside the detection response task, a standard workload measure. Sixty-five participants completed a task in which stationary stimuli were tar;geted using a mouse, with a within-subjects factor of task workload based on the number of targets to be hovered over with the mouse (one/two), and a between-subjects factor based on whether both targets (exhaustive) or just one target (minimum-time) needed to be hovered over to complete a trial when two targets were presented. Mouse movement onset times were slower and mouse movement trajectories exhibited more submovements when two targets were presented, than when one target was presented. Responses to the detection response task were also slower in this condition, indicating higher cognitive workload. However, these differences were only found for participants in the exhaustive condition, suggesting those in the minimum-time condition were not affected by the presence of the second target. Mouse movement trajectory results agreed with other measures of workload and task performance. Our findings suggest this analysis can be applied to workload assessments in real-world scenarios.  
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  Series Volume Series Issue Edition  
  ISSN 1044-7318 ISBN Medium  
  Area Expedition Conference  
  Notes (up) Approved no  
  Call Number Serial 117  
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Author Mimouni-Bloch, A.; Shaklai, S.; Levin, M.; Ingber, M.; Karolitsky, T.; Grunbaum, S.; Friedman, J. pdf  url
doi  openurl
  Title Developmental and acquired brain injury have opposite effects on finger coordination in children Type Journal Article
  Year 2023 Publication Frontiers in Human Neuroscience Abbreviated Journal Front. Hum. Neurosci.  
  Volume 17 Issue Pages 1083304  
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  Series Volume Series Issue Edition  
  ISSN 1662-5161 ISBN Medium  
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  Notes (up) Approved no  
  Call Number Serial 119  
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Author Dempsey-Jones, H.; Wesselink, D.B.; Friedman, J.; Makin, T.R. pdf  url
doi  openurl
  Title Organized Toe Maps in Extreme Foot Users Type Journal Article
  Year 2019 Publication Cell Reports Abbreviated Journal Cell Reports  
  Volume 28 Issue 11 Pages 2748-2756.e4  
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  Abstract Although the fine-grained features of topographic maps in the somatosensory cortex can be shaped by everyday experience, it is unknown whether behavior can support the expression of somatotopic maps where they do not typically occur. Unlike the fingers, represented in all primates, individuated toe maps have only been found in non-human primates. Using 1-mm resolution fMRI, we identify organized toe maps in two individuals born without either upper limb who use their feet to substitute missing hand function and even support their profession as foot artists. We demonstrate that the ordering and structure of the artists’ toe representation mimics typical hand representation. We further reveal “hand-like” features of activity patterns, not only in the foot area but also similarly in the missing hand area. We suggest humans may have an innate capacity for forming additional topographic maps that can be expressed with appropriate experience.  
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  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2211-1247 ISBN Medium  
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  Notes (up) doi: 10.1016/j.celrep.2019.08.027 Approved no  
  Call Number Serial 99  
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